The meaning of “Let’s Go Darwin” is the answer to “Let’s Go Brandon” aka Fuck Joe Biden chants by the GOP Republicans.
“Let’s Go Darwin“ is a counterattack to the anti-vax, anti-max crowd. Most likely Republicans and Let’s Go Brandon #FJB (anti Biden) people.
The late Charles Darwin is the scientist / biologist credited with the theory of evolution, natural selection, and the survival of the fittest.
So, logically, if you refuse a mask and a shot. Then “Let’s Go Darwin! Do your job.“